Yamada’s Textbook of Gastroenterology

Sixth Edition

Edited by Daniel K. Podolsky,
Michael Camilleri, J. Gregory Fitz,
Anthony N. Kalloo, Fergus Shanahan, Timothy C. Wang

References

Anorectal diseases

1. GordonPH, NivatvongsS(eds). Principles and Practice of Surgery for the Colon, Rectum, and Anus. St Louis, MO: Quality Medical Publishing, 1999.

2. JohansonJF, SonnenbergA. Constipation is not a risk factor for hemorrhoids: a case‐control study of potential etiological agents. Am J Gastroenterol1994;89:1981.

3. JohannssonHO, GrafW, PahlmanL. Bowel habits in hemorrhoid patients and normal subjects. Am J Gastroenterol2005;100:401. CrossRef

4. HaasPA, FoxTAJr, HaasGP. The pathogenesis of hemorrhoids. Dis Colon Rectum1984;27:442. CrossRef

5. CataldoP, EllisCN, GregorcykS, et al.Practice parameters for the management of hemorrhoids (revised). Dis Colon Rectum2005;48:189. CrossRef

6. GreensponJ, WilliamsSB, YoungHA, et al.Thrombosed external hemorrhoids: outcome after conservative or surgical management. Dis Colon Rectum2004;47:1493. CrossRef

7. KluiberRM, WolffBG. Evaluation of anemia caused by hemorrhoidal bleeding. Dis Colon Rectum1994;37:1006. CrossRef

8. Alonso‐CoelloP, MillsE, Heels‐AnsdellD, et al.Fiber for the treatment of hemorrhoids complications: a systematic review and meta‐analysis. Am J Gastroenterol2006;101:181. CrossRef

9. MisraMC. Imlitemsu. Drug treatment of haemorrhoids. Drugs2005;65:1481. CrossRef

10. BarronJ. Office ligation treatment of hemorrhoids. Dis Colon Rectum1963;6:109. CrossRef

11. MacRaeHM, McLeodRS. Comparison of hemorrhoidal treatments: a meta‐analysis. Can J Surg1997;40:14.

12. O'ReganPJ. Disposable device and a minimally invasive technique for rubber band ligation of hemorrhoids. Dis Colon Rectum1999;42:683. CrossRef

13. DickeyW, GarrettD. Hemorrhoid banding using videoendoscopic anoscopy and a single‐handed ligator: an effective, inexpensive alternative to endoscopic band ligation. Am J Gastroenterol2000;95:1714. CrossRef

14. ShanmugamV, ThahaMA, RabindranathKS, et al.Rubber band ligation versus excisional haemorrhoidectomy for haemorrhoids. Cochrane Database Syst Rev2005;(3):CD005034.

15. GearhartSL. Symptomatic hemorrhoids. Adv Surg2004;38:167.

16. RandallGM, JensenDM, MachicadoGA, et al.Prospective randomized comparative study of bipolar versus direct current electrocoagulation for treatment of bleeding internal hemorrhoids. Gastrointest Endosc1994;40:403. CrossRef

17. TjandraJJ, ChanMKY. Systematic review on the procedure for prolapse and hemorrhoids (stapled hemorrhoidopexy). Dis Colon Rectum2007;50:878. CrossRef

18. JayaramanS, ColquhounPH, MalthanerRA. Stapled hemorrhoidopexy is associated with a higher long‐term recurrence rate of internal hemorrhoids compared with conventional excisional hemorrhoid surgery. Dis Colon Rectum2007;50:1297. CrossRef

19. CormanML, GravieJF, HagerT, et al.Stapled haemorrhoidopexy: a consensus position paper by an international working party – indications, contraindications and technique. Colorectal Dis2003;5:304. CrossRef

20. Nunoo‐MensahJW, KaiserAM. Stapled hemorrhoidectomy. Am J Surg2005;190:127. CrossRef

21. HoskingSW, SmartHL, JohnsonAG, et al.Anorectal varices, haemorrhoids, and portal hypertension. Lancet1989;i:349. CrossRef

22. WangTF, LeeFY, TsaiYT, et al.Relationship of portal pressure, anorectal varices and hemorrhoids in cirrhotic patients. J Hepatol1992;15:170. CrossRef

23. DhimanRK, SaraswatVA, ChoudhuriG, et al.Endosonographic, endoscopic, and histologic evaluation of alterations in the rectal venous system in patients with portal hypertension. Gastrointest Endosc1999;49:218. CrossRef

24. HoskingSW, JohnsonAG. Bleeding anorectal varices – a misunderstood condition. Surgery1988;104:70.

25. YehTJr, McGuireHHJr. Intractable bleeding from anorectal varices relieved by inferior mesenteric vein ligation. Gastroenterology1994;107:1165.

26. ShibataD, BrophyDP, GordonFD, et al.Transjugular intrahepatic portosystemic shunt for treatment of bleeding ectopic varices with portal hypertension. Dis Colon Rectum1999;42:1581. CrossRef

27. OryG, SpahrL, MegevandJM, et al.The long‐term efficacy of the intrahepatic portosystemic shunt (TIPS) for the treatment of bleeding anorectal varices in cirrhosis. A case report and review of the literature. Digestion2001;64:261. CrossRef

28. ParksAG. Pathogenesis and treatment of fistula‐in‐ano. Br Med J1961;1:463. CrossRef

29. RamanujamPS, PrasadML, AbcarianH, et al.Perianal abscesses and fistulas. A study of 1023 patients. Dis Colon Rectum1984;27:593. CrossRef

30. ParksAG, GordonPH, HardcastleJD. A classification of fistula‐in‐ano. Br J Surg1976;63:1. CrossRef

31. VasilevskyCA, GordonPH. The incidence of recurrent abscesses or fistula‐in‐ano following anorectal suppuration. Dis Colon Rectum1984;27:126. CrossRef

32. SchwartzDA, WiersemaMJ, DudiakKM, et al.A comparison of endoscopic ultrasound, magnetic resonance imaging, and exam under anesthesia for evaluation of Crohn's perianal fistulas. Gastroenterology2001;121:1064. CrossRef

33. WestRL, ZimmermanDD, DwarkasingS, et al.Prospective comparison of hydrogen peroxide‐enhanced three‐dimensional endoanal ultrasonography and endoanal magnetic resonance imaging of perianal fistulas. Dis Colon Rectum2003;46:1407. CrossRef

34. BubrickMP, HitchcockCR. Necrotizing anorectal and perineal infections. Surgery1979;86:655.

35. CorfitsenMT, HansenCP, ChristensenTH, et al.Anorectal abscesses in immunosuppressed patients. Eur J Surg1992;158:51.

36. BarnesSG, SattlerFR, BallardJO. Perirectal infections in acute leukemia. Improved survival after incision and debridement. Ann Intern Med1984;100:515. CrossRef

37. SchoutenWR, van VroonhovenTJ. Treatment of anorectal abscess with or without primary fistulectomy. Results of a prospective randomized trial. Dis Colon Rectum1991;34:60. CrossRef

38. GraceRH, HarperIA, ThompsonRG. Anorectal sepsis: microbiology in relation to fistula‐in‐ano. Br J Surg1982;69:401. CrossRef

39. WilliamsJG, RothenbergerDA, NemerFD, et al.Fistula‐in‐ano in Crohn's disease. Results of aggressive surgical treatment. Dis Colon Rectum1991;34:378. CrossRef

40. FryRD, ShemeshEI, KodnerIJ, et al.Techniques and results in the management of anal and perianal Crohn's disease. Surg Gynecol Obstet1989;168:42.

41. LibermanH, ThorsonA. Anal sepsis and fistula. In: ZuidemaGD, YeoCJ(eds). Shackelford's Surgery of the Alimentary Tract. Philadelphia: WB Saunders; 2002; 388.

42. CintronJR, ParkJJ, OrsayCP, et al.Repair of fistulas‐in‐ano using fibrin adhesive: long‐term follow‐up. Dis Colon Rectum2000;43:944, discussion 949. CrossRef

43. Garcia‐AguilarJ, BelmonteC, WongWD, et al.Anal fistula surgery. Factors associated with recurrence and incontinence. Dis Colon Rectum1996;39:723. CrossRef

44. VasilevskyCA. Fistula‐in‐ano and abscess. In: BeckDE, WexnerSD(eds). Fundamentals of Anorectal Surgery. London: WB Saunders; 1998; 152.

45. SandbornWJ, FazioVW, FeaganBG, et al.AGA technical review on perianal Crohn's disease. Gastroenterology2003;125:1508. CrossRef

46. PresentDH, KorelitzBI, WischN, et al.Treatment of Crohn's disease with 6‐mercaptopurine. A long‐term, randomized, double‐blind study. N Engl J Med1980;302:981. CrossRef

47. Peyrin‐BirouletL, DeltenreP, De SurayN, et al.Efficacy and safety of tumor necrosis factor antagonists in Crohn's disease: meta‐analysis of placebo‐controlled trials. Clin Gastroenterol Hepatol2008;6:644. CrossRef

48. PresentDH, RutgeertsP, TarganS, et al.Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med1999;340:1398. CrossRef

49. RennaS, OrlandoA, CottoneM. Randomized controlled trials in perianal Crohn's disease. Rev Recent Clin Trials2012;7:297.

50. GoldbergSM, GordonPH. Treatment of rectal prolapse. Clin Gastroenterol1975;4:489.

51. AbcarianH, PembertonJH. Prolapse and procidentia. In: ZuidemaGD, YeoCJ, PembertonJH(eds). Shackelford's Surgery of the Alimentary Tract. Philadelphia: WB Saunders; 2002; 410.

52. WattsJD, RothenbergerDA, BulsJG, et al.The management of procidentia. 30 years' experience. Dis Colon Rectum1985;28:96. CrossRef

53. HiltunenKM, MatikainenM, AuvinenO, et al.Clinical and manometric evaluation of anal sphincter function in patients with rectal prolapse. Am J Surg1986;151:489. CrossRef

54. MyersJO, RothenbergerDA. Sugar in the reduction of incarcerated prolapsed bowel. Report of two cases. Dis Colon Rectum1991;34:416. CrossRef

55. BachooP, BrazzelliM, GrantA. Surgery for complete rectal prolapse in adults. Cochrane Database Syst Rev2000;(2):CD001758.

56. CadedduF, SileriP, GrandeM, et al.Focus on abdominal rectopexy for full‐thickness rectal prolapse: meta‐analysis of literature. Tech Coloproctol2012;16:37. CrossRef

57. MadoffRD, FleshmanJW. AGA technical review on the diagnosis and care of patients with anal fissure. Gastroenterology2003;124:235. CrossRef

58. FaroukR, DuthieGS, MacGregorAB, et al.Sustained internal sphincter hypertonia in patients with chronic anal fissure. Dis Colon Rectum1994;37:424. CrossRef

59. BrownAC, SumfestJM, RozwadowskiJV. Histopathologyof the internal anal sphincter in chronic anal fissure. Dis Colon Rectum1989;32:680. CrossRef

60. SchoutenWR, BrielJW, AuwerdaJ, et al.Ischaemic nature of anal fissure. Br J Surg1996;83:63. CrossRef

61. SchoutenWR, BrielJW, AuwerdaJ. Relationship between anal pressure and anodermal blood flow. The vascular pathogenesis of anal fissures. Dis Colon Rectum1994;37:664. CrossRef

62. MelangeM, ColinJF, van WymerscT, et al.Anal fissure: correlation between symptoms and manometry before and after surgery. Int J Colorectal Dis1992;7:108. CrossRef

63. DodiG, BogoniF, InfantinoA, et al.Hot or cold in anal pain? A study of the changes in internal anal sphincter pressure profiles. Dis Colon Rectum1986;29:248. CrossRef

64. JensenSL. Treatment of first episodes of acute anal fissure: prospective randomised study of lignocaine ointment versus hydrocortisone ointment or warm sitz baths plus bran. Br Med J (Clin Res Ed)1986;292:1167. CrossRef

65. LoderPB, KammMA, NichollsRJ, et al.“Reversible chemical sphincterotomy” by local application of glyceryl trinitrate. Br J Surg1994;81:1386. CrossRef

66. CarapetiEA, KammMA, PhillipsRK. Randomized controlled trial of topical phenylephrine in the treatment of faecal incontinence. Br J Surg2000;87:38. CrossRef

67. AltomareDF, RinabliM, PetrolinoM, et al.Reliability of electrophysiologic anal tests in predicting the outcome of sacral nerve modulation for fecal incontinence. Dis Colon Rectum2004;47:853. CrossRef

68. NelsonRL, ThomasK, MorganJ, et al.Non surgical therapy for anal fissure. Cochrane Database Syst Rev2012;(2):CD003431.

69. AntropoliC, PerrottiP, RubinoM, et al.Nifedipine for local use in conservative treatment of anal fissures: preliminary results of a multicenter study. Dis Colon Rectum1999;42:1011. CrossRef

70. JonasM, NealKR, AbercrombieJF, et al.A randomized trial of oral vs. topical diltiazem for chronic anal fissures. Dis Colon Rectum2001;44:1074. CrossRef

71. EzriT, SusmallianS. Topical nifedipine vs. topical glyceryl trinitrate for treatment of chronic anal fissure. Dis Colon Rectum2003;46:805. CrossRef

72. SajidMS, WhitehousePA, SainsP, et al.Systematic review of the use of topical diltiazem compared with glyceryltrinitrate for the nonoperative management of chronic anal fissure. Colorectal Dis2013;15:19. CrossRef

73. MariaG, CassettaE, GuiD, et al.A comparison of botulinum toxin and saline for the treatment of chronic anal fissure. N Engl J Med1998;338:217. CrossRef

74. BrisindaG, MariaG, BentiroglioA, et al.A comparison of injections of botulinum toxin and topical nitroglycerin ointment for the treatment of chronic anal fissure [erratum appears in N Engl J Med 1999;341:624]. N Engl J Med1999;341:65. CrossRef

75. JostWH. One hundred cases of anal fissure treated with botulin toxin: early and long‐term results. Dis Colon Rectum1997;40:1029. CrossRef

76. ArroyoA, PerezF, SerranoP, et al.Long‐term results of botulinum toxin for the treatment of chronic anal fissure: prospective clinical and manometric study. Int J Colorectal Dis2005;20:267. CrossRef

77. BrisindaG, CadedduF, BrandaraF, et al.Treating chronic anal fissure with botulinum neurotoxin. Nat Clin Pract Gastroenterol Hepatol2004;1:82. CrossRef

78. YiannakopoulouE. Botulinum toxin and anal fissure: efficacy and safety systematic review. Int J Colorectal Dis2012;27:1. CrossRef

79. NelsonR. Non surgical therapy for anal fissure [update of Cochrane Database Syst Rev 2003(4):CD003431; PMID 14583976]. Cochrane Database Syst Rev2006;(4):CD003431.

80. Garcia‐GraneroE, SanahujaA, Garcia‐ArmengolJ, et al.Anal endosonographic evaluation after closed lateral subcutaneous sphincterotomy. Dis Colon Rectum1998;41:598. CrossRef

81. Garcia‐AguilarJ, BelmonteC, WongWD, et al.Open vs. closed sphincterotomy for chronic anal fissure: long‐term results. Dis Colon Rectum1996;39:440. CrossRef

82. LittlejohnDR, NewsteadGL. Tailored lateral sphincterotomy for anal fissure. Dis Colon Rectum1997;40:1439. CrossRef

83. SohnN, EisenbergNM, WeinsteinM, et al.Precise anorectal sphincter dilatation – its role in the therapy of anal fissures. Dis Colon Rectum1992;35:322. CrossRef

84. SohnN, WeinsteinMA. Anal dilatation for anal fissures. Semin Colon Rectal Surg1997;8:17.

85. NelsonRL, ChattopadhyayA, BrooksW, et al.Operative procedures for fissure in ano. Cochrane Database Syst Rev2011;(11):CD002199.

86. MilsomJW, MazierWP. Classification and management of postsurgical anal stenosis. Surg Gynecol Obstet1986;163:60.

87. LibermanH, ThorsonAG. How I do it. Anal stenosis. Am J Surg2000;179:325. CrossRef

88. LinaresL, MoreiraLF, AndrewsH, et al.Natural history and treatment of anorectal strictures complicating Crohn's disease. Br J Surg1988;75:653. CrossRef

89. VaizeyCJ, van den BogaerdeJB, EmmanuelAV, et al.Solitary rectal ulcer syndrome. Br J Surg1998;85:1617. CrossRef

90. MadiganMR, MorsonBC. Solitary ulcer of the rectum. Gut1969;10:871. CrossRef

91. ErtemD, AcarY, KaraaEK, et al.A rare and often unrecognized cause of hematochezia and tenesmus in childhood: solitary rectal ulcer syndrome. Pediatrics2002;110:e79. CrossRef

92. WomackNR, WilliamsNS, HolmfieldJH, et al.Pressure and prolapse – the cause of solitary rectal ulceration. Gut1987;28:1228. CrossRef

93. HalliganS, NichollsRJ, BartramCI. Evacuation proctography in patients with solitary rectal ulcer syndrome: anatomic abnormalities and frequency of impaired emptying and prolapse. AJR Am J Roentgenol1995;164:91. CrossRef

94. KangYS, KammMA, NichollsRJ. Solitary rectal ulcer and complete rectal prolapse: one condition or two?Int J Colorectal Dis1995;10:87. CrossRef

95. KangYS, KammMA, EngelAF, et al.Pathology of the rectal wall in solitary rectal ulcer syndrome and complete rectal prolapse. Gut1996;38:587. CrossRef

96. EckardtVF, KanzlerG, RemmeleW. Anorectal ergotism: another cause of solitary rectal ulcers. Gastroenterology1986;91:1123.

97. CroweJ, StellatoTA. Radiation‐induced solitary rectal ulcer. Dis Colon Rectum1985;28:610. CrossRef

98. TsengCA, ChenLT, TsaiKB, et al.Acute hemorrhagic rectal ulcer syndrome: a new clinical entity? Report of 19 cases and review of the literature. Dis Colon Rectum2004;47:895, discussion 903. CrossRef

99. GilraneTB, OrchardJL, Al‐AssaadZA. A benign rectal ulcer penetrating into the prostate – diagnosis by prostate‐specific antigen. Gastrointest Endosc1987;33:467. CrossRef

100. van den Brandt‐GradelV, HuibregtseK, TytgatGN. Treatment of solitary rectal ulcer syndrome with high‐fiber diet and abstention of straining at defecation. Dig Dis Sci1984;29:1005. CrossRef

101. JarrettME, EmmanuelAV, VaizeyCJ, et al.Behavioural therapy (biofeedback) for solitary rectal ulcer syndrome improves symptoms and mucosal blood flow. Gut2004;53:368. CrossRef

102. SitzlerPJ, KammMA, NichollsRJ, et al.Long‐term clinical outcome of surgery for solitary rectal ulcer syndrome. Br J Surg1998;85:1246. CrossRef

103. BishopPR, NowickiMJ. Current treatment options: nonsurgical therapy for solitary rectal ulcer syndrome. Gastroenterology2002;5:215.

104. StoppinoV, CuomoR, TontiP, et al.Argon plasma coagulation of hemorrhagic solitary rectal ulcer syndrome. J Clin Gastroenterol2003;37:392. CrossRef

105. ZargarSA, KhurooMS, MahajanR. Sucralfate retention enemas in solitary rectal ulcer. Dis Colon Rectum1991;34:455. CrossRef

106. PerryS, ShawC, McGrotherC, et al.Prevalence of faecal incontinence in adults aged 40 years or more living in the community. Gut2002;50:480. CrossRef

107. BharuchaA. Fecal incontinence. Gastroenterology2003;124:1672. CrossRef

108. BharuchaAE, ZinsmeisterAR, LockeGR, et al.Prevalence and burden of fecal incontinence: a population based study in women. Gastroenterology2005;129:42. CrossRef

109. BharuchaAE, ZinsmeisterAR, LockeGR, et al.Symptoms and quality of life in community women with fecal incontinence. Clin Gastroenterol Hepatol2006;4:1004. CrossRef

110. BassottiG, CrowellMD, WhiteheadWE. Contractile activity of the human colon: lessons from 24 hour studies. Gut1993;34:129. CrossRef

111. SunWM, DonnellyTC, ReadNW. Utility of a combined test of anorectal manometry, electromyography, and sensation in determining the mechanism of “idiopathic” faecal incontinence. Gut1992;33:807. CrossRef

112. BharuchaAE, FletcherJG, HarperCM, et al.Relationship between symptoms and disordered continence mechanisms in women with idiopathic fecal incontinence. Gut2005;54:546. CrossRef

113. BartoloDC, JarrattJA, ReadMG, et al.The role of partial denervation of the puborectalis in idiopathic faecal incontinence. Br J Surg1983;70:664. CrossRef

114. Fernandez‐FragaX, AzpirozF, MalageladaJR. Significance of pelvic floor muscles in anal incontinence. Gastroenterology2002;123:1441. CrossRef

115. HarewoodGC, CoulieB, CamilleriM, et al.Descending perineum syndrome: audit of clinical and laboratory features and outcome of pelvic floor retraining. Am J Gastroenterol1999;94:126. CrossRef

116. BartoloDC, ReadNW, JarrattJA, et al.Differences in anal sphincter function and clinical presentation in patients with pelvic floor descent. Gastroenterology1983;85:68.

117. BuserWD, MinerPBJr. Delayed rectal sensation with fecal incontinence. Successful treatment using anorectal manometry. Gastroenterology1986;91:1186.

118. HaademK, DahlstromJA, LingL. Anal sphincter competence in healthy women: clinical implications of age and other factors. Obstet Gynecol1991;78:823.

119. SiproudhisL, El AbkariM, El AlaouiM, et al.Low rectal volumes in patients suffering from fecal incontinence: what does it mean?Aliment Pharmacol Ther2005;22:989. CrossRef

120. ChanCL, LunnissPJ, WangD, et al.Rectal sensorimotor dysfunction in patients with urge faecal incontinence: evidence from prolonged manometric studies. Gut2005;54:1263. CrossRef

121. CorsettiM, CesanaB, BhooriS, et al.Rectal hyperreactivity to distention in patients with irritable bowel syndrome: role of distention rate. Clin Gastroenterol Hepatol2004;2:49. CrossRef

122. PriorA, MaxtonDG, WhorwellPJ. Anorectal manometry in irritable bowel syndrome: differences between diarrhoea and constipation predominant subjects. Gut1990;31:458. CrossRef

123. PriorA, SorialE, SunWM, et al.Irritable bowel syndrome: differences between patients who show rectal sensitivity and those who do not. Eur J Gastroenterol Hepatol1993;5:343. CrossRef

124. LynnPA, OlssonC, ZagorodnyukV, et al.Rectal intraganglionic laminar endings are transduction sites of extrinsic mechanoreceptors in the guinea pig rectum. Gastroenterology2003;125:786. CrossRef

125. MillerR, BartoloDC, CerveroF, et al.Anorectal sampling: a comparison of normal and incontinent patients. Br J Surg1988;75:44. CrossRef

126. SultanAH, KammMA, HudsonCN, et al.Anal‐sphincter disruption during vaginal delivery. N Engl J Med1993;329:1905. CrossRef

127. BharuchaAE, ZinsmeisterAR, LockeGR, et al.Risk factors for fecal incontinence: a population based study in women. Am J Gastroenterol2006;101:1305. CrossRef

128. BharuchaAE, ZinsmeisterAR, SchleckCD, et al.Bowel disturbances are the most important risk factors for late onset fecal incontinence: a population‐based case‐control study in women. Gastroenterology2010;139:1559. CrossRef

129. BharuchaAE, FletcherJG, MeltonLJ, et al.Obstetric trauma, pelvic floor injury and fecal incontinence: a population‐based case‐control study. Am J Gastroenterol2012;107:902. CrossRef

130. ParelladaCM, MillerAS, WilliamsonME, et al.Paradoxical high anal resting pressures in men with idiopathic fecal seepage. Dis Colon Rectum1998;41:593. CrossRef

131. RaoSS, OzturkR, StessmanM. Investigation of the pathophysiology of fecal seepage. Am J Gastroenterol2004;99:2204. CrossRef

132. CaruanaBJ, WaldA, HindsJP, et al.Anorectal sensory and motor function in neurogenic fecal incontinence. Comparison between multiple sclerosis and diabetes mellitus. Gastroenterology1991;100:465.

133. LewisSJ, HeatonKW. Stool form scale as a useful guide to intestinal transit time. Scand J Gastroenterol1997;32:920. CrossRef

134. EngelAF, KammMA, BartramCI, et al.Relationship of symptoms in faecal incontinence to specific sphincter abnormalities. Int J Colorectal Dis1995;10:152. CrossRef

135. ChanCL, ScottSM, WilliamsNS, et al.Rectal hypersensitivity worsens stool frequency, urgency, and lifestyle in patients with urge fecal incontinence. Dis Colon Rectum2005;48:134. CrossRef

136. RockwoodTH. Incontinence severity and QOL scales for fecal incontinence. Gastroenterology2004;126:S106. CrossRef

137. DiamantNE, KammMA, WaldA, et al.AGA technical review on anorectal testing techniques. Gastroenterology1999;116:735. CrossRef

138. AgachanF, PfeiferJ, WexnerSD. Defecography and proctography. Results of 744 patients. Dis Colon Rectum1996;39:899. CrossRef

139. ShorvonPJ, McttughsS, DiamantNE, et al.Defecography in normal volunteers: results and implications. Gut1989;30:1737. CrossRef

140. BharuchaAE, FletcherJG, SeideB, et al.Phenotypic variation in functional disorders of defecation. Gastroenterology2005;128:1199. CrossRef

141. RociuE, StokerJ, EijkemansMJ, et al.Fecal incontinence: endoanal US versus endoanal MR imaging. Radiology1999;212:453. CrossRef

142. BrielJW, StokerJ, RociuE, et al.External anal sphincter atrophy on endoanal magnetic resonance imaging adversely affects continence after sphincteroplasty. Br J Surg1999;86:1322. CrossRef

143. CheongDM, VaccaroCA, SalangaVD, et al.Electrodiagnostic evaluation of fecal incontinence. Muscle Nerve1995;18:612. CrossRef

144. BharuchaAE, SeideB, FoxJC, et al.Day‐to‐day reproducibility of anorectal sensorimotor assessments in healthy subjects. Neurogastroenterol Motil2004;16:241. CrossRef

145. HullT, GieseC, WexnerSD, et al.Long‐term durability of sacral nerve stimulation therapy for chronic fecal incontinence. Dis Colon Rectum2013;56:234. CrossRef

146. SkoogSM, BharuchaAE. Dietary fructose and gastrointestinal symptoms: a review. Am J Gastroenterol2004;99:2046. CrossRef

147. ReadM, ReadNW, BarberDC, et al.Effects of loperamide on anal sphincter function in patients complaining of chronic diarrhea with fecal incontinence and urgency. Dig Dis Sci1982;27:807. CrossRef

148. PalmerKR, CorbettCL, HoldsworthCD. Double‐blind cross‐over study comparing loperamide, codeine and diphenoxylate in the treatment of chronic diarrhea. Gastroenterology1980;79:1272.

149. SciarrettaG, FurnoA, MazzoniM, et al.Post‐cholecystectomy diarrhea: evidence of bile acid malabsorption assessed by SeHCAT test. Am J Gastroenterol1992;87:1852.

150. SantoroGA, EitanBZ, PrydeA, et al.Open study of low‐dose amitriptyline in the treatment of patients with idiopathic fecal incontinence. Dis Colon Rectum2000;43:1676. CrossRef

151. CamilleriM, NorthcuttAR, KongS, et al.Efficacy and safety of alosetron in women with irritable bowel syndrome: a randomised, placebo‐controlled trial. Lancet2000;355:1035. CrossRef

152. BharuchaAE, DornSD, LemboA, et al.American Gastroenterological Association medical position statement on constipation. Gastroenterologygy2013;144:211. CrossRef

153. BharuchaAE, PembertonJH, LockeGR. AGA practice guideline on constipation: technical review. Gastroenterology2013;144:218. CrossRef

154. NortonC, ChelvanayagamS, Wilson‐BarnettJ, et al.Randomized controlled trial of biofeedback for fecal incontinence. Gastroenterology2003;125:1320. CrossRef

155. HeymenS, ScarlettY, JonesK, et al.Randomized controlled trial shows biofeedback to be superior to alternative treatments for fecal incontinence. Dis Colon Rectum2009;52:1730. CrossRef

156. BharuchaAE, FletcherJG, CamilleriM, et al.Effects of clonidine in women with fecal incontinence. Clin Gastroenterol Hepatol2014; In press. 10.1016/j.cgh.2013.06.035.

157. CheungO, WaldA. Review article: the management of pelvic floor disorders. Aliment Pharmacol Ther2004;19:481. CrossRef

158. ChapmanAE, GeerdesB, HewettP, et al.Systematic review of dynamic graciloplasty in the treatment of faecal incontinence. Br J Surg2002;89:138. CrossRef

159. WexnerSD, BaetenC, BaileyR, et al.Long‐term efficacy of dynamic graciloplasty for fecal incontinence. Dis Colon Rectum2002;45:809. CrossRef

160. WongW, CongliosiSM, SpencerMP, et al.The safety and efficacy of the artificial bowel sphincter for fecal incontinence: results from a multicenter cohort study. Dis Colon Rectum2002;45:1139. CrossRef

161. MundyL, MerlinTL, MaddernGJ, et al.Systematic review of safety and effectiveness of an artificial bowel sphincter for faecal incontinence. Br J Surg2004;91:665. CrossRef

162. ShirranE, BrazzelliM. Absorbent products for the containment of urinary and/or faecal incontinence in adults. Cochrane Database Syst Rev2000;(2):CD001406.

163. ChristiansenJ, Roed‐PetersenK. Clinical assessment of the anal continence plug. Dis Colon Rectum1993;36:740. CrossRef

164. GiamundoP, WelberA, WeissEG, et al.The procon incontinence device: a new nonsurgical approach to preventing episodes of fecal incontinence. Am J Gastroenterol2002;97:2328. CrossRef

165. WexnerSD, CollerJA, DevroedeG, et al.Sacral nerve stimulation for fecal incontinence: results of a 120‐patient prospective multicenter study. Ann Surg2010;251:441. CrossRef

166. LeroiA‐M, ParcY, LehurP‐A, et al.Efficacy of sacral nerve stimulation for fecal incontinence: results of a multicenter double‐blind crossover study. Ann Surg2005;242:662. CrossRef

167. PattonV, WiklendtL, ArkwrightJW, et al.The effect of sacral nerve stimulation on distal colonic motility in patients with faecal incontinence. Br J Surg2013;100:959. CrossRef

168. GrafW, MellgrenA, MatzelKE, et al.Efficacy of dextranomer in stabilised hyaluronic acid for treatment of faecal incontinence: a randomised, sham‐controlled trial. Lancet2011;377:997. CrossRef

169. NortonC. Treating faecal incontinence with bulking‐agent injections. Lancet2011;377:971. CrossRef

170. MaedaY, LaurbergS, NortonC. Perianal injectable bulking agents as treatment for faecal incontinence in adults. Cochrane Database Syst Rev2013;(2): CD007959.

171. EfronJE, CormanML, FleshmanJ, et al.Safety and effectiveness of temperature‐controlled radio‐frequency energy delivery to the anal canal (Secca procedure) for the treatment of fecal incontinence. Dis Colon Rectum2003;46:1606, discussion 1616. CrossRef

172. MarkellKW, BillinghamRP. Pruritus ani: etiology and management. Surg Clin North Am2010;90:125. CrossRef

173. MurieJA, SimAJ, MackenzieI. The importance of pain, pruritus and soiling as symptoms of haemorrhoids and their response to haemorrhoidectomy or rubber band ligation. Br J Surg1981;68:247. CrossRef

174. PowellFC, PerryHO. Pruritus ani: could it be malignant?Geriatrics1985;40:89.

175. DodiG, PironeE, BettinA, et al.The mycotic flora in proctological patients with and without pruritus ani. Br J Surg1985;72:967. CrossRef

176. SilvermanSH, YoungsDJ, AllanA, et al.The fecal microflora in pruritus ani. Dis Colon Rectum1989;32:466. CrossRef

177. SmithLE, HenrichsD, McCullahRD. Prospective studies on the etiology and treatment of pruritus ani. Dis Colon Rectum1982;25:358. CrossRef

178. HejnaM, ValencakJ, RadererM. Anal pruritus after cancer chemotherapy with gemcitabine. N Engl J Med1999;340:655. CrossRef

179. FriendWG. The cause and treatment of idiopathic pruritus ani. Dis Colon Rectum1977;20:40. CrossRef

180. FaroukR, DuthieGS, PrydeA, et al.Abnormal transient internal sphincter relaxation in idiopathic pruritus ani: physiological evidence from ambulatory monitoring. Br J Surg1994;81:603. CrossRef

181. SilvestriDL, BarmettlerS. Pruritus ani as a manifestation of systemic contact dermatitis: resolution with dietary nickel restriction. Dermatitis2011;22:50.

182. LysyJ, Sistiery‐IttahM, IsraelitY, et al.Topical capsaicin – a novel and effective treatment for idiopathic intractable pruritus ani: a randomised, placebo controlled, crossover study. Gut2003;52:1323. CrossRef

183. WaldA. Functional anorectal and pelvic pain. Gastroenterol Clin North Am2001;30:243. CrossRef

184. GrantSR, SalvatiEP, RubinRJ. Levator syndrome: an analysis of 316 cases. Dis Colon Rectum1975;18:161. CrossRef

185. BharuchaAE, WaldA, EnckP, et al.Functional anorectal disorders. Gastroenterology2006;130:1510. CrossRef

186. GrimaudJC, BouvierM, NaudyB, et al.Manometric and radiologic investigations and biofeedback treatment of chronic idiopathic anal pain. Dis Colon Rectum1991;34:690. CrossRef

187. ChiarioniG, NardoA, VantiniI, et al.Biofeedback is superior to electrogalvanic stimulation and massage for treatment of levator ani syndrome. Gastroenterology2010;138:1321. CrossRef

188. RaoSSC, PaulsonJ, MataM, et al.Clinical trial: effects of botulinum toxin on Levator ani syndrome – a double‐blind, placebo‐controlled study. Aliment Pharmacol Ther2009;29:985. CrossRef

189. BarnesPR, HawleyPR, PrestonDM, et al.Experience of posterior division of the puborectalis muscle in the management of chronic constipation. Br J Surg1985;72:475. CrossRef

190. ThompsonWG. Proctalgia fugax. Dig Dis Sci1981;26:1121. CrossRef

191. EckardtVF, DodtO, KanzlerG, et al.Anorectal function and morphology in patients with sporadic proctalgia fugax. Dis Colon Rectum1996;39:755. CrossRef

192. KammMA, HoyleCH, BurleighDE, et al.Hereditary internal anal sphincter myopathy causing proctalgia fugax and constipation. A newly identified condition. Gastroenterology1991;100:805.

193. CelikAF, KatsinelosP, ReadNW, et al.Hereditary proctalgia fugax and constipation: report of a second family. Gut1995;36:581. CrossRef

194. SwainR. Oral clonidine for proctalgia fugax. Gut1987;28:1039. CrossRef

195. EckardtVF, DodtO, KanzlerG, et al.Treatment of proctalgia fugax with salbutamol inhalation. Am J Gastroenterol1996;91:686.

196. GuyRJ, KammMA, MartinJE. Internal anal sphincter myopathy causing proctalgia fugax and constipation: further clinical and radiological characterization in a patient. Eur J Gastroenterol Hepatol1997;9:221. CrossRef

197. YoonK, ChoiSK, AmarnathLA, et al.Caudal epidural block with methylprednisone acetate in the management of chronic idiopathic rectal pain. Coloproctology1994;16:161.

198. ThieleGH. Coccygodynia: cause and treatment. Dis Colon Rectum1963;6:422. CrossRef

199. MaigneJY, TamaletB. Standardized radiologic protocol for the study of common coccygodynia and characteristics of the lesions observed in the sitting position. Clinical elements differentiating luxation, hypermobility, and normal mobility. Spine1996;21:2588. CrossRef

200. FogelGR, CunninghamPY3rd, EssesSI. Coccygodynia: evaluation and management. J Am Acad Orthop Surg2004;12:49.

201. EvansPJ, LloydJW, JackTM. Cryoanalgesia for intractable perineal pain. J R Soc Med1981;74:804.

202. ClarkeDL, BuccimazzaI, AndersonFA, et al.Colorectal foreign bodies. Colorectal Dis2005;7:98. CrossRef

203. BuschDB, StarlingJR. Rectal foreign bodies: case reports and a comprehensive review of the world's literature. Surgery1986;100:512.

204. OoiBS, HoYH, EuKW, et al.Management of anorectal foreign bodies: a cause of obscure anal pain. Aust N Z J Med1998;68:852. CrossRef

205. LakeJP, EssaniR, PetroneP, et al.Management of retained colorectal foreign bodies: predictors of operative intervention. Dis Colon Rectum2004;47:1694. CrossRef

206. BerghoffKR, FranklinMEJr. Laparoscopic‐assisted rectal foreign body removal: report of a case. Dis Colon Rectum2005;48:1975. CrossRef

207. AbcarianH. Rectal trauma. Gastroenterol Clin North Am1987;16:115.

208. IvaturyRR, LicataJ, GunduzY, et al.Management options in penetrating rectal injuries. Am Surg1991;57:50.

209. EinsteinMH, KadishAS. Anogenital neoplasia in AIDS. Curr Opin Oncol2004;16:455. CrossRef

210. QualtersJR, LeeNC, SmithRA, et al.Breast and cervical cancer surveillance, United States, 1973–1987. MMWR CDC Surveill Summ1992;41:1.

211. ZakiSR, JuddR, CoffieldLM, et al.Human papillomavirus infection and anal carcinoma. Retrospective analysis by in situ hybridization and the polymerase chain reaction. Am J Pathol1992;140:1345.

212. PalmerJG, ScholefieldJH, CoatesPJ, et al.Anal cancer and human papillomaviruses. Dis Colon Rectum1989;32:1016. CrossRef

213. StanleyMA, WinderDM, SterlingJC, et al.HPV infection, anal intra‐epithelial neoplasia (AIN) and anal cancer: current issues. BMC Cancer2012;12:398. CrossRef

214. PalefskyJM, GiulianoAR, GoldstoneS, et al.HPV vaccine against anal HPV infection and anal intraepithelial neoplasia. NEJM 20111576;365:85.

215. RyanDP, ComptonCC, MayerRJ. Carcinoma of the anal canal. N Engl J Med2000;342:792. CrossRef

216. PalefskyJM, HollyEA, HogeboomCJ, et al.Virologic, immunologic, and clinical parameters in the incidence and progression of anal squamous intraepithelial lesions in HIV‐positive and HIV‐negative homosexual men. J Acquir Immune Defic Syndr1998;17:314. CrossRef

217. PalefskyJM, HollyEA, RalstonML, et al.Anal squamous intraepithelial lesions in HIV‐positive and HIV‐negative homosexual and bisexual men: prevalence and risk factors. J Acquir Immune Defic Syndr1998;17:320. CrossRef

218. MarfingTE, AbelME, GallagherDM. Perianal Bowen's disease and associated malignancies. Results of a survey. Dis Colon Rectum1987;30:782. CrossRef

219. MarchesaP, FazioVW, OliartS, et al.Perianal Bowen's disease: a clinicopathologic study of 47 patients. Dis Colon Rectum1997;40:1286. CrossRef

220. GoldieSJ, KuntzKM, WeinsteinMC, et al.Cost‐effectiveness of screening for anal squamous intraepithelial lesions and anal cancer in human immunodeficiency virus‐negative homosexual and bisexual men. Am J Med2000;108:634. CrossRef

221. ScholefieldJH, HarrisD, RadcliffeA. Guidelines for management of anal intraepithelial neoplasia. Colorectal Dis2011;13(Suppl 1):3. CrossRef

222. CummingsBJ. Current management of epidermoid carcinoma of the anal canal. Gastroenterol Clin North Am1987;16:125.

223. AdamYG, EfronG. Current concepts and controversies concerning the etiology, pathogenesis, diagnosis, and treatment of malignant tumors of the anus. Surgery1987;101:253.

224. GrodskyL. Unsuspected anal cancer discovered after minor anorectal surgery. Dis Colon Rectum1967;10:471. CrossRef

225. CataldoPA, MacKeiganJM. The necessity of routine pathologic evaluation of hemorrhoidectomy specimens. Surg Gynecol Obstet1992;174:302.

226. FrischM, OlsonJH, BauatzA, et al.Benign anal lesions and the risk of anal cancer. N Engl J Med1994;331:300. CrossRef

227. SurawiczCM, CritchlowC, SayerJ, et al.High grade anal dysplasia in visually normal mucosa in homosexual men: seven cases. Am J Gastroenterol1995;90:1776.

228. ParksA. Squamous carcinoma of the anal canal. Ann Gastroenterol Hepatol1981;17:103.

229. SimpsonJA, ScholefieldJH. Diagnosis and management of anal intraepithelial neoplasia and anal cancer. BMJ2011;343:d6818. CrossRef

230. NigroND. An evaluation of combined therapy for squamous cell cancer of the anal canal. Dis Colon Rectum1984;27:763. CrossRef

231. CummingsBJ, KeaneTJ, O'SullivanB, et al.Epidermoid anal cancer: treatment by radiation alone or by radiation and 5‐fluorouracil with and without mitomycin C. Int J Radiat Oncol Biol Phys1991;21:1115. CrossRef

232. Anon. Epidermoid anal cancer: results from the UKCCCR randomised trial of radiotherapy alone versus radiotherapy, 5‐fluorouracil, and mitomycin. UKCCCR Anal Cancer Trial Working Party. UK Co‐ordinating Committee on Cancer Research. Lancet1996;348:1049. CrossRef

233. McCarterMD, QuanSH, BusamK, et al.Long‐term outcome of perianal Paget's disease. Dis Colon Rectum2003;46:612. CrossRef

234. WeinstockMA. Epidemiology and prognosis of anorectal melanoma. Gastroenterology1993;104:174.

235. ThibaultC, SagarP, NivatvongsS, et al.Anorectal melanoma – an incurable disease?Dis Colon Rectum1997;40:661. CrossRef

236. BradyMS, KavoliusJP, QuanSH. Anorectal melanoma. A 64‐year experience at Memorial Sloan‐Kettering Cancer Center. Dis Colon Rectum1995;38:146. CrossRef

237. NielsenOV, JensenSL. Basal cell carcinoma of the anus – a clinical study of 34 cases. Br J Surg1981;68:856. CrossRef

238. SollaJA, RothenbergerDA. Chronic pilonidal disease. An assessment of 150 cases. Dis Colon Rectum1990;33:758. CrossRef

239. SondenaaK, AndersenE, NesvikI, et al.Patient characteristics and symptoms in chronic pilonidal sinus disease. Int J Colorectal Dis1995;10:39. CrossRef

240. BillinghamRP, IslerJT, KimminsMH, et al.The diagnosis and management of common anorectal disorders. Curr Probl Surg2004;41:586. CrossRef

241. AydedeH, ErhanY, SakaryaA, et al.Comparison of three methods in surgical treatment of pilonidal disease. Aust N Z J Med2001;71:362. CrossRef

242. AkcaT, ColakT, UstunsoyB, et al.Randomized clinical trial comparing primary closure with the Limberg flap in the treatment of primary sacrococcygeal pilonidal disease. Br J Surg2005;92:1081. CrossRef

243. HolzerB, GrussnerU, BrucknerB, et al.Efficacy and tolerance of a new gentamicin collagen fleece (Septocoll) after surgical treatment of a pilonidal sinus. Colorectal Dis2003;5:222. CrossRef

244. LundJN, LevesonSH. Fibrin glue in the treatment of pilonidal sinus: results of a pilot study. Dis Colon Rectum2005;48:1094. CrossRef

245. WisemanMC. Hidradenitis suppurativa: a review. Dermatol Ther2004;17:50. CrossRef

246. LebwohlB, SapadinAN. Infliximab for the treatment of hidradenitis suppurativa. J Am Acad Dermatol2003;49(5 Suppl):S275. CrossRef

247. BharuchaAE. Outcome measures for fecal incontinence: anorectal structure and function. Gastroenterology2004;26:S90. CrossRef